Erythroid blast crisis in chronic myelogenous leukemia
نویسندگان
چکیده
منابع مشابه
Erythroid blast crisis in chronic myelogenous leukemia.
Blood or bone marrow specimens from 22 patients with chronic myelogenous leukemia in blast crisis were studied for the surface expression of glycophorin-A, a marker for early erythroid differentiation. The leukemic blasts were stained with rabbit anti-glycophorin-A antiserum. The glycophorin-A molecules detected by the rabbit antiserum were identified by polyacrylamide slab gel electrophoresis ...
متن کاملFlow Cytometry in Chronic Myelogenous Leukemia Blast Crisis
Background: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder due to BCR-ABL1 translocation. Patients showing transformation into blast crisis (BC) have poorer treatment response and prognosis. Methods: A retrospective study was conducted in the department of Pathology, Maulana Azad Medical College, New Delhi, India, over a time period of 5 years (2014-2019) to evaluate the ...
متن کاملPromyelocytic blast crisis of chronic myelogenous leukemia.
A 26-year-old male was evaluated for chest pain and was found to have a white cell count of 63 000 per cubic millimeter, hemoglobin 10.5 g/dL, platelets 102 000 per L, with 18% blasts and promyelocytes (panel A). Bone marrow was hypercellular, with promyelocytes and myeloblasts (panel B), some with deeply clefted nuclei. This was morphologically consistent with acute promyelocytic leukemia hype...
متن کاملErythroid blast crisis of chronic myeloid leukemia.
70-year old woman was admitted with a diagnosis of pyelonephritis. The physical examination showed her to be lethargic and febrile (39°C). There was no liver or spleen enlargement. Laboratory findings were as follows: white blood cell count: 25310, hemoglobin level: 11.2 g/dL, platelet count: 41310/L, lacticodehydrogenase level: 4,100 IU/L (normal value < 350); erythrocyte sedimentation rate: 9...
متن کاملErythroid blast crisis in chronic myelogenous leukemia: Case report and review of literature.
Chronic myelogenous leukemia (CML) is a myeloproliferative disorder where over a period of time 15-20% of patients show blastic transformation with majority transforming into acute myeloid leukemia, most of which are of granulocytic lineage. Erythroid blast phase of CML is relatively rare with the incidence ranging from 0-10%. Further the incidence of acute erythroid leukemia by itself is fairl...
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ژورنال
عنوان ژورنال: Blood
سال: 1983
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v62.3.591.bloodjournal623591